Background: Post-stroke fatigue (PSF) is one of the most challenging clinical consequences to manage after stroke as no effective treatment has been developed. However, the mechanisms of PSF remain unclear.
Aims: This study aimed to replicate Vecchio et al (2017) using resting-state EEG in stroke patients suffering from varying degrees of fatigue to describe the functional organisation within sensory and motor networks.
Methods: Resting-state eyes-open EEG was recorded in 22 strokesurvivors. Upper limb functional tests (grip strength, Nine Hole Peg Test), symbol digit modalities test (SDTM), anxiety and depression scale (HADS), Fatigue Severity Scale (FSS-7), state fatigue, and Neurological Fatigue Index (NFI-stroke) were measured. Graph theory was used to calculate the small-world (SW) index. SW was calculated in four separate networks, motor and sensory within the left and right hemispheres. Exact low-resolution brain electromagnetic tomography (eLORETA) was applied using seven frequency bands (delta, theta, alpha1, alpha2, beta1, beta2, and gamma).
Results: Correlation analysis demonstrated a positive association between SW in the right motor network in beta2 band and higher FSS-7 score and a negative correlation between SW in the left sensory network in alpha1 and higher state fatigue.
Conclusion: Beta oscillations have been associated with top-down processes which are crucial for perceptual inference and alpha oscillations are involved in sensorimotor information processing. The interaction between the top-down and bottom-up processes, and perceived error explains the sensory attenuation model of fatigue. Our results were consistent this model of fatigue as stroke survivors had difficulty in attenuating the sensory input leading to higher perceived effort.
Citación recomendada (normas APA)
Ana María Gómez Carvajal, "Sensory and motor dynamics in post-stroke fatigue", Colombia:-, 2020. Consultado en línea en la Biblioteca Digital de Bogotá (https://www.bibliotecadigitaldebogota.gov.co/resources/3711887/), el día 2025-06-16.
