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Surgery Versus Endoscopic Therapies For Early Cancer And High-Grade Dysplasia In The Esophagus: A Systematic Review

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Año de publicación 2016
Idioma Inglés
Publicado por Arquivos de Gastroenterologia; Vol.53, No. 1

Descripción: Background: Esophageal cancer occurs as a local disease in 22% of cases, and a minority of this disease is limited to the mucosa or submucosa (early lesions). Endoscopic mucosal resection, endoscopic submucosal dissection, photodynamic therapy, laser therapy, and argon plasma coagulation have emerged as alternatives to surgical resection for early lesions. Objective: The aim of this systematic review is to identify studies that statistically compare survival, disease-free survival, morbidity and mortality associated with the procedure, and mortality associated with cancer in the endoscopic versus surgical therapies. Results: The survival rates after 3 and 5 years were different and exhibited superiority with the surgical therapies over time. Endoscopy is superior in the control of mortality related to cancer with a high rate of disease recurrence. With regard to the comorbidity and the mortality associated with the procedure, endoscopy is superior. Conclusion: There is no evidence from clinical trials. In this systematic review, surgical therapies showed superiority for survival, and endoscopic therapies showed superiority in the control of mortality related to cancer with a high rate of disease recurrence; also, for the comorbidity and the mortality associated with the procedure, endoscopy is superior. Prospective, controlled trials with large sample sizes are necessary to confirm the results of the current analysis.
Citación recomendada (normas APA)
: Fabio Alberto; Hourneaux de Moura Castillo Bustamante, "Surgery Versus Endoscopic Therapies For Early Cancer And High-Grade Dysplasia In The Esophagus: A Systematic Review", -:Arquivos de Gastroenterologia; Vol.53, No. 1, 2016. Consultado en línea en la Biblioteca Digital de Bogotá (https://www.bibliotecadigitaldebogota.gov.co/resources/2089196/), el día 2025-05-11.

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- Medicina
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Fuente Biblioteca Virtual Banco de la República
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Año de publicación 2016
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Surgery Versus Endoscopic Therapies For Early Cancer And High-Grade Dysplasia In The Esophagus: A Systematic Review

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