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- 18 de Julio de 2019
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[Oficios de Andrés Rodríguez al Gobernador de Novita]
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[Oficios de Andrés Rodríguez al Gobernador de Novita]
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Piketty comes to South Africa
Abstract:
One of the most valuable features of Capital and Ideology is its concern to take history seriously and consider how the emergence of different political and economic regimes relate to discourses about fairness and justice across time. This paper pushes this agenda further by acknowledging that the experience of a few developed nations should not be taken as the template for the generalized study of inequality dynamics across time and space. In this paper, we interrogate Piketty's analysis and policy proposals against specificities that are central to understanding the production and reproduction of inequalities within South Africa. We reflect on the South African case, the structure of inequality and its changes since 1994. We review a battery of policy interventions that have been implemented to address inequality in the last 25 years. We emphasize that the long shadow cast by centuries of colonialism and various forms of apartheid strongly affirm Piketty's emphasis on understanding history. But this is both affirmation and critique given the foundational, imbedded impact that this specific legacy has had on post-apartheid society and its policies. Piketty is aware that the levels of inequality in South Africa are so high that this is “unknown territory.” We map out some of this territory to reveal how these extreme initial wealth and racial inequities inform the reproduction of inequalities in all dimensions and undermine well intentioned policies. We claim that understanding extractive histories, imbedded wealth inequalities, and complex social and political institutions allows us to understand and confront some of the reasons why even in light of progressive policies, many of which are in line with the proposals from Piketty, government interventions have thus far failed to reduce inequality.
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Piketty comes to South Africa
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Severe ipsilateral musculoskeletal involvement in a Cornelia de Lange patient with a novel NIPBL mutation
Abstract:
Cornelia de Lange Syndrome (CdLS) is a congenital autosomal dominant (NIPBL, SMC3 and RAD21) or Xlinked (SMC1A and HDAC8) disorder characterized by facial dysmorphism, pre and postnatal growth retardation, developmental delay and/or intellectual disability, and multiorgan involvement. Musculoskeletal malformations are usually bilateral and affect mainly the upper limbs; the range goes from brachyclinodactyly to severe reduction defects. Instead lower extremities are usually less and mildly involved. Here, we report on a 3-year-old Senegalese boy with typical craniofacial CdLS features, pre and postnatal growth retardation, atrial septal defect, developmental delay and right ipsilateral limb malformations, consistent with oligodactyly of the 3rd and 4th fingers, tibial agenesis and fibula hypoplasia.
Exome sequencing and Sanger sequencing showed a novel missense mutation in NIPBL gene (c.6647A>G; p.(Tyr2216Cys)), which affects a conserved residue located within NIPBL HEAT repeat elements.
Pyrosequencing analysis of NIPBL gene, disclosed similar levels of wild-type and mutated alleles in DNA and RNA samples from all tissues analyzed (oral mucosa epithelial cells, peripheral blood leukocytes and fibroblasts). These findings indicated the absence of somatic mosaicism, despite of the segmental asymmetry of the limbs, and confirmed biallelic expression for NIPBL transcripts, respectively. Additionally, conditions like Split-hand/foot malformation with long-bone deficiency secondary to duplication of BHLHA9 gene have been ruled out by the array-CGH and MLPA analysis. To our knowledge, this is the first CdLS patient described with major ipsilateral malformations of both the upper and lower extremities, that even though this finding could be due to a random event, expands the spectrum of limb reduction defects in CdLS.
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Severe ipsilateral musculoskeletal involvement in a Cornelia de Lange patient with a novel NIPBL mutation
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Extraction and partial characterisation of antioxidant pigment produced by Chryseobacterium sp. kr6
Abstract:
Pigments synthesised by Chryseobacterium sp. kr6 growing on feather waste were extracted and characterised. The pigment extract was characterised by KOH test, UV–vis, CIELAB colour system, HPLCDAD-
MS, FTIR and its antioxidant capacity was evaluated. A positive bathochromic shift was observed when kr6 colonies or pigment extracts were subjected to alkaline solution (20% KOH) and a λmax
at 450 nm was detected for acetone extracts, although no typical fine structure of carotenoids was detected in the electomagnetic spectra. The HPLC profile of the extracted pigment showed that the
compound has three different peaks with λmax near 450 nm. The FTIR analysis shows some principal functional groups from a flexirubinlike molecule. The pigmented compound also presents antioxidant
activity evaluated by the scavenging of the ABTS radical.
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Extraction and partial characterisation of antioxidant pigment produced by Chryseobacterium sp. kr6
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Natural Pigments of Microbial Origin
Abstract:
The world demands new solutions and products to be used as dyes for industrial applications. Microbial pigments represent an eco-friendly alternative as they can be produced in large amounts through biotechnological processes and do not present environmental risks, as they are easily decomposable. Moreover, some of these metabolites are recognized for their biological activities, which qualify them for potential uses as food colorants and nutraceuticals, protecting against degenerative diseases related with oxidative stress. Because of their genetic simplicity as compared with plants, microorganisms may be a better source to understand biosynthetic mechanisms and to be engineered for producing high pigment yields. Despite the origin of the pigmented microorganism,it seems very important to develop protocols using organic industrial residues and agricultural byproducts as substrates for pigment production and fi nd novel green strategies for rapid pigment extraction. This review looks for the most recent studies that describe microbial pigments from microalgae, fungi, and bacteria. In particular, the underexploited tools of omics science such as proteomics and metabolomics are addressed. The use of techniques involving mass spectrometry, allows to identify different protein and metabolite profi les that may be associated with a variety of biotechnologically-relevant pathways of pigment synthesis.
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Natural Pigments of Microbial Origin
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¿Son la misión y visión verdaderos promotores de ventaja competitiva e innovación?
Resumen:
Durante años, expertos en Estrategia han resaltado la importancia de definir claramente el marco estratégico de una empresa debido a que éste le permite crear su identidad, propósito y dirección. Asimismo, porque a la vez dicho marco sirve como instrumento para apropiarse de una mayor porción de valor creado a partir de, por ejemplo, la implementación de más y mejores prácticas de innovación empresarial. Sin embargo, ¿es realmente determinante la construcción acuciosa de un marco estratégico para efectos de generar resultados adecuados en términos de innovación y competitividad? El presente trabajo tiene como propósito abordar dicho cuestionamiento. Para ello se pretende desplegar un planteamiento teórico y conceptual sobre el impacto de la calidad del marco estratégico (i.e., misión y visión organizacional) sobre la creación de ventaja competitiva y posterior consecución de una cultura de innovación en las organizaciones. Para ello, en principio se desarrollará una revisión sistemática sobre el impacto de estos dos componentes sobre los resultados organizacionales, y se propondrá el vínculo teórico que puede existir entre las variables involucradas. Los resultados obtenidos serán proposiciones teóricas susceptibles de ser comprobadas empíricamente en un estudio posterior.
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¿Son la misión y visión verdaderos promotores de ventaja competitiva e innovación?
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Oficios de don Aparicio Vidaurrázaga cuando vino a Popayán
Abstract:
Using the theoretical-methodological perspective based on experience frameworks, this paper aims at analyzing and understanding the way in which organizations communicate aspects that are related to occupational safety and health. In this sense, we carry out an analysis of the narratives related to this topic and propose a diagnosis mechanism to subjectively measure the burden of the regulatory, strategic, and moral frameworks of these narratives. A panel of Latin American experts applied a three-round Delphi analysis on five case studies in Colombia to illustrate how this mechanism works. In addition to the use of a robust research paradigm, this work contributes by proposing a scheme capable of presenting the motivations and interests of occupational safety and health professionals in perspective, finding imbalances in the way relevant information is transmitted through official messages and channels. Therefore, its use is susceptible to study in this and other areas of knowledge of the organizational discipline, and its adoption could be worthwhile in order to generate more and better knowledge in this regard.
Resumen:
Haciendo uso de la perspectiva teórico-metodológica basada en los marcos de la experiencia, el presente trabajo tiene como propósito analizar y entender la forma en la que, usualmente, se comunican los aspectos relacionados con la seguridad y la salud en el trabajo en el contexto organizacional. En este sentido, se despliega un análisis sobre las narrativas propias de esta temática y se propone un mecanismo de diagnóstico para medir subjetivamente la carga de los marcos reglamentario, estratégico y moral de dichas narrativas. Un análisis Delphi de tres rondas aplicado por un panel de expertos latinoamericanos sobre cinco casos de estudio en Colombia ilustra la manera en la que el mecanismo en mención puede funcionar. Adicional al uso de un paradigma investigativo robusto, el trabajo contribuye, toda vez que propone un esquema capaz de exponer en perspectiva, las motivaciones y los intereses de los profesionales de la seguridad y salud en el trabajo, encontrando desequilibrios en cuanto a la forma de transmitir información relevante por medio de mensajes y canales oficiales. Por tanto, su uso es susceptible de estudio en esta y otras áreas del conocimiento de la disciplina organizacional, y su adopción podría valer la pena en aras de generar más y mejor conocimiento al respecto.
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Enmarcando la seguridad y la salud en el trabajo: entre lo reglamentario, lo estratégico y lo moral
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Río Amazonas, un mar de agua dulce
Artículo que relata parte de la historia del río Amazonas y sus afluentes, las etnias indígenas que conviven con el río y el entorno de algunas zonas aledañas a este en Perú, Colombia y Brasil.
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Río Amazonas, un mar de agua dulce
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Oficios del gobierno de Popayán al de la Unión
Responsables de los documentos: Cabal, José María; Cabal, Francisco; Montúfar, Carlos; Montalvo, Miguel José
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Oficios del gobierno de Popayán al de la Unión
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Oficios de Sámano y otros españoles para servir a la historia de la revolución de la Nueva Granada
Responsables de los documentos: Erazo, Ventura; Solarte, Francisco; Satizabal, José María; Muñoz, Simón; Sámano, Juan; Rodríguez, Antonio; Cabal, José María; Montes, Toribio; Warleta, Francisco
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Oficios de Sámano y otros españoles para servir a la historia de la revolución de la Nueva Granada