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Imagen de apoyo de  Business Plan for Amasonaz Eco. Organic Frozen Fruit Import, commercialization and distribution from Colombia to Spain

Business Plan for Amasonaz Eco. Organic Frozen Fruit Import, commercialization and distribution from Colombia to Spain

Por: Luis Eduardo; Sanchez Lastra Echeverri Duque | Fecha: 2022

Abstract: The Pulp Fruit Imports and commercialization from Colombia to Spain Business Plan is a project that aims to support the solution of 3 main challenges in Colombia (Organic food waste, Ex-warriors from peace accords signature returning to society trough farming opportunities and life quality improvement to current farmers) while needs from Spanish consumers are satisfied. This last ones, after the pandemic, increased their awareness of consuming responsibly, which means protect their health and the environment at the same time the want enjoy a convenient and natural drink to join their meals and that allows them to continue with their life rhythm. For that reason, Amazonas Eco offers a range of exotic fruits that are transformed into pulp fruit through a local strategic partner with Bio certifications, then transported to Spain to be sold through the customer's preferred channels. This business plan includes a bibliographical study that uses Colombian and Spanish available data from different authorities combined with a filed work survey conducted to Spanish consumers that was used afterwards to develop case of study of Marketing Analysis using Statistical tools such as Multiple regression and Conjoint Analysis. These both supported to define main market trends, STEEP and Porter Analysis and marketing strategy (Segmentation, Price, Placement and Promotion). Furthermore interviews were done to a current exported and producer of pulp fruit from Colombia and to and Spanish expert profesor in logistics, these last interviews supported to define business model, Operational model and Financial forecasts. The principal market trends are explained into 3 main categories: 1. Sourcing: Exports from Colombia to the EU in organic food grew from 2019 to 2020 by 35% (European Commission) meaning almost 28.000 additional tons per year. 2. Consumption: the imports of Spain for the frozen fruit market have an average annual growth between 2012 and 2016 of 7,5% jumping from 219.000 MUSD to 291.000 MUSD in those years. (Zambrano Achi and Pozo Burgos). 3. SOM: Initially Amazonas Eco will focus in Cataluña, therefore the market size is given by the population size and the average price and consumption of nectars and fresh juices and soft drinks. Combined the total expected market size would be 75 MEUR (“Últimos datos de consumo alimentario”). After defining a reachable scope in a SOM and Colombia's production capacity the company expects sales of 100 tons/year with an income of 1.2 MEUR. The Operational model is build under 3 main pillars: Farmers, Pulp fruit producer in Colombia, then imports to Spain followed by storage in a warehouse and distributed through a third part logistics service provider reaching Organic markets (preferred channel of main segment) and consumers. Financial model is done by identifying needed assets and operational expenses using marketing analysis to defined expected sales and required inventory. With this financial statements are build for 3 years followed by Net present Value exercise and break even point. This company will request 390,000 EUR of equity. According to the assumptions the NPV of the project is positive therefore, it is decided to go forward with it. The IRR is 15% meaning that NPV will be negative when the cost of capital is higher than this. Break Even point is reachable at 75.500 kg in one year keeping the cost structure. Statement of financial positioning, comprehensive income statement and cash flow statement are built under a conservative model with the assumptions given above where an organic growth is expected for this business holding positive income and cash flow since year 1.
Fuente: Biblioteca Virtual Banco de la República Formatos de contenido: Tesis
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  • Economía

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Business Plan for Amasonaz Eco. Organic Frozen Fruit Import, commercialization and distribution from Colombia to Spain

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Imagen de apoyo de  Framework for Water Management in the Food-Energy-Water (FEW) Nexus in Mixed Land-Use Watersheds in Colombia

Framework for Water Management in the Food-Energy-Water (FEW) Nexus in Mixed Land-Use Watersheds in Colombia

Por: Camilo; Gitau Torres Pardo | Fecha: 2020

Abstract: The food-energy-water (FEW) nexus approach has emerged as an alternative for managing these resources more efficiently. Work from studies conducted in the FEW nexus in Latin America is scarce in the scholarly literature. This study aims to develop a framework for water management at the FEW Nexus, with a focus on Colombia. The study focuses on a typical mixed land-use watershed in the Andean region with specific objectives being to: (1) characterize the watershed with respect to land use, climate, water resources, and other factors pertinent to the nexus; (2) explore the relationship between factors in the FEW nexus that may affect water management in terms of quality and availability; and (3) propose a methodology for conducting a FEW Nexus analysis for watersheds located in the Andean region. The results indicate that the Pereira/Dosquebradas urban area has a significant impact on the FEW nexus components in the Otun River Watershed (ORW). Subsequently, an urban FEW nexus framework is proposed for its implementation at the watershed.
Fuente: Biblioteca Virtual Banco de la República Formatos de contenido: Artículos
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Framework for Water Management in the Food-Energy-Water (FEW) Nexus in Mixed Land-Use Watersheds in Colombia

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Imagen de apoyo de  Challenges and benefits of heritage languages in the home, a family language policy perspective. Three case studies of Spanish speaker’s families in New Zealand = Retos y beneficios de la lengua de herencia en casa. El caso de tres familias de habla hispana en Nueva Zealand: una política del lenguaje familiar en perspectiva

Challenges and benefits of heritage languages in the home, a family language policy perspective. Three case studies of Spanish speaker’s families in New Zealand = Retos y beneficios de la lengua de herencia en casa. El caso de tres familias de habla hispana en Nueva Zealand: una política del lenguaje familiar en perspectiva

Por: Lizeth Andrea Ceron Becerra | Fecha: 2018

Abstract: This study shows that parental beliefs, management and practices are not the only considerations. Societal influences determine parental language practices and management, which in turn delimits their children’s linguistic development. The decision that parents take perpetuate children’s linguistic development, however, in reality societal influences are determining parental language practices and management. The external and internal relationships permeate parents’ language decisions whereby subtle intergenerational heritage language loss takes place. Therefore, the struggle in maintaining their heritage language in the home domain has become a challenge for the parents. This study uncovers plentiful evidence that the language experiences of the three Latino-English families are challenging. Families consistently stated that it is an intensive responsibility raising their children bilingually in New Zealand. Despite there being a high awareness of the value of Spanish as an international language, and a number of cultural events where Latino-hispanic culture is evident, there is relatively insufficient peripheral support. It is evident in this study that in order to support families in their attempt to raise their children as bilingual there should be an integrated and encompassed socio-educational support. Otherwise, as it was found in this research, external influences will continue affecting migrant children's heritage language learning. Overall, the following list summarizes the challenges that families face in the attempt to raise their children as bilinguals. Only one parent speaks the language. As it was embedded in this research that the macro, meso and micro level influences the family language practices. For the macro: Lack of governmental support and a solid language policy for minority languages in New Zealand. Meso: Societal challenges/influences, lack of community support, lack of school language integration, lack of cultural and language appreciation at school. Micro: Lack of time to teach/translate the language to their spouses. Lack of commitment to speak the language from both parents, due to the lack of school and community language integration there is child's resistant attitudes to learn the language.
Fuente: Biblioteca Virtual Banco de la República Formatos de contenido: Tesis
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Challenges and benefits of heritage languages in the home, a family language policy perspective. Three case studies of Spanish speaker’s families in New Zealand = Retos y beneficios de la lengua de herencia en casa. El caso de tres familias de habla hispana en Nueva Zealand: una política del lenguaje familiar en perspectiva

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Imagen de apoyo de  Evaluation of sampling frequency impact on the accuracy of water quality status as determined considering different water quality monitoring objectives

Evaluation of sampling frequency impact on the accuracy of water quality status as determined considering different water quality monitoring objectives

Por: Camilo; Gitau Torres Pardo | Fecha: 2022

Abstract: Water quality sampling is a key element in tracking water quality monitoring objectives. However, frequencies adapted by different agencies might not be sufficient to provide an accurate indication of water quality status. In this study, data from low- and high-resolution water quality datasets were analyzed to determine the extent to which monitoring objectives could be achieved with different sampling frequencies, with a view to providing recommendations and best practices for water quality monitoring frequency in places with limited resources with which to implement a high-frequency monitoring plan. Water quality data from two watersheds (Maumee River and Raisin River) located in the Western Lake Erie Basin (WLEB) were used since these watersheds have consistent records over substantial periods of time, and the water quality data available have a high resolution (at least daily). The water quality constituents analyzed included suspended solids (SS), total phosphorus (TP), soluble reactive phosphorus (SRP), and nitrate + nitrite (NO2+3). Sources of pollutants for watersheds located in the WLEB include contributions from point sources like discharges from sewage treatment plants and non-point sources such as agricultural and urban storm runoff. Weekly, bi-weekly, monthly, and seasonal datasets were created from the original datasets, following different sampling rules based on the day of the week, week of the month, and month of the year. The resulting datasets were then compared to the original dataset to determine how the sampling frequency would affect the results obtained in a water quality assessment when different monitoring objectives are considered. Results indicated that constituents easily transported by water (such as sediments and nutrients) require more than 50 samples/year to provide a small error (< 10%) with a confidence interval of 95%. Monthly and seasonal sampling were found appropriate to report a stream’s prevailing water quality status and statistical properties. However, these resolutions might not be sufficient to capture longterm trends, in which case bi-weekly samples would be preferable. Limitations of lowresolution sampling frequency could be overcome by including rainfall events and random sampling during specific time windows as part of the monitoring plan.
Fuente: Biblioteca Virtual Banco de la República Formatos de contenido: Artículos
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Evaluation of sampling frequency impact on the accuracy of water quality status as determined considering different water quality monitoring objectives

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Imagen de apoyo de  Evaluation of sampling frequency impact on the accuracy of water quality status as determined considering different water quality monitoring objectives

Evaluation of sampling frequency impact on the accuracy of water quality status as determined considering different water quality monitoring objectives

Por: Camilo; Gitau Torres Pardo | Fecha: 2022

Abstract: Water quality sampling is a key element in tracking water quality monitoring objectives. However, frequencies adapted by different agencies might not be sufficient to provide an accurate indication of water quality status. In this study, data from low- and high-resolution water quality datasets were analyzed to determine the extent to which monitoring objectives could be achieved with different sampling frequencies, with a view to providing recommendations and best practices for water quality monitoring frequency in places with limited resources with which to implement a high-frequency monitoring plan. Water quality data from two watersheds (Maumee River and Raisin River) located in the Western Lake Erie Basin (WLEB) were used since these watersheds have consistent records over substantial periods of time, and the water quality data available have a high resolution (at least daily). The water quality constituents analyzed included suspended solids (SS), total phosphorus (TP), soluble reactive phosphorus (SRP), and nitrate + nitrite (NO2+3). Sources of pollutants for watersheds located in the WLEB include contributions from point sources like discharges from sewage treatment plants and non-point sources such as agricultural and urban storm runoff. Weekly, bi-weekly, monthly, and seasonal datasets were created from the original datasets, following different sampling rules based on the day of the week, week of the month, and month of the year. The resulting datasets were then compared to the original dataset to determine how the sampling frequency would affect the results obtained in a water quality assessment when different monitoring objectives are considered. Results indicated that constituents easily transported by water (such as sediments and nutrients) require more than 50 samples/year to provide a small error (< 10%) with a confidence interval of 95%. Monthly and seasonal sampling were found appropriate to report a stream’s prevailing water quality status and statistical properties. However, these resolutions might not be sufficient to capture longterm trends, in which case bi-weekly samples would be preferable. Limitations of lowresolution sampling frequency could be overcome by including rainfall events and random sampling during specific time windows as part of the monitoring plan.
Fuente: Biblioteca Virtual Banco de la República Formatos de contenido: Artículos
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Evaluation of sampling frequency impact on the accuracy of water quality status as determined considering different water quality monitoring objectives

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Imagen de apoyo de  Bio-inspired Topologies to Enhance the Mechanical Strength of Co-cured Ti-CFRP Hybrid Joints

Bio-inspired Topologies to Enhance the Mechanical Strength of Co-cured Ti-CFRP Hybrid Joints

Por: Breyner Andrés Castro Castillo | Fecha: 2022

Abstract: The main aim of this study is to investigate utilising root improve the interfacial strength of pin-like integrated hybrid composite architectures to metal structures. Joints are critical elements in aircraft structures and require special consideration due to their vital role in the structural integrity of airframes. Although bonded and bolted systems are used commonly in engineering applications, pinning technologies have shown tremendous potential for hybrid joints. Nonetheless, exploring complex pin geometries has been challenging when considering associated manufacturing techniques. Using pre-preg constrains the topography of the pin, while vacuum resin infusion offers more possibilities to manufacture complex hybrid joints. This study develops an experimental methodology to fabricate hybrid joints with arbitrary pin geometry using Selective Laser Melting (SLM) and resin infusion techniques. First, titanium parts with four inclination angles of 0°, 20°, 45° and 80° were fabricated using the SLM method, and their surface roughness was examined using a profilometer. Then, dry unidirectional carbon fabrics were stacked into pins in a hand layup process followed by epoxy infusion in a vacuum chamber. The cross-section of the fabricated joints was inspected employing an optical microscope, SEM and ?CT-scanner. The pin angle shape of the resin and fibre alignment impacted the geometry and rich area in the insertion region. Manufacturing defects such as pores were present in the composite with a high density closer to the titanium composite bondline. Despite those setbacks, resin-infused composites were integrated into highly tilted pins such as 45° or 80°. This precedent demonstrated that root like pins could also be co-cured with composites. The effect of pin angle on the mechanical performance of hybrid joints was experiment ally investigated. The load-displacement response of various specimens was recorded while joints were subjected to pull-off tensile loading. Experimental results showed how the pin angle affects the stiffness, strength and strain energy of joints. Damage initiation and propagation in the hybrid joints were also investigated by examining the fracture surfaces and the relationship between damage mechanisms and pin angles. Significant matrix crushing was realised in joints with 45° and 80° inclined pins with p in rupture only observed in the latter. Furthermore, a numerical study was conducted to explore the response of multiple root-like pin geometries. A 2D model was developed and validated for parametric study based on the experimentally measured interfacial strength. This bidimensional model accurately captured the experimental load-displacement curves for joints under tensile load. After calibration, the model was used to study the effect of three branches geometrical features of a rootlike pin on the mechanical behaviour of the hybrid joint. It was demonstrated that the diameter, length and location of side branches play a vital role in the failure behaviour of joints by affecting the stress distribution in composite adherend. Based on the findings from this study, it can be concluded that the integration of complex pin shapes and composite are likely using resin infusion techniques. Moreover, root like pins with optimised topology can be incorporated into hybrid joints to enhance bonding strength and failure behaviour.
Fuente: Biblioteca Virtual Banco de la República Formatos de contenido: Tesis
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Bio-inspired Topologies to Enhance the Mechanical Strength of Co-cured Ti-CFRP Hybrid Joints

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Imagen de apoyo de  Determinación de la huella hídrica y modelación de la producción de biomasa de cultivos forrajeros a partir del agua en la sabana de Bogotá (Colombia)

Determinación de la huella hídrica y modelación de la producción de biomasa de cultivos forrajeros a partir del agua en la sabana de Bogotá (Colombia)

Por: César Augusto Terán Chaves | Fecha: 2015

Abstract: Summary The main objective was aimed at determining the biomass production from water based on water relations, levels of water consumption of the species, and climate variables that affect the formation of biomass and soil present and specifically it focused on two forage crops which were Forage Oats (Avena sativa L.) and ryegrass (Lolium perenne). The solution to the problem is based on AquaCrop model (FAO) Steduto et al, (2009) which was recently proposed for the determination of both biomass and agricultural production from water transpired by herbaceous species, this is gather scientific and technological advances on the effect of water in the estimation of crop production has been achieved in recent years. In the present research we have identified key variables AquaCrop model input for the two species mentioned, through field research conducted using the methodology gradient Hanks et al., (1980), and a new methodology proposal for determining water stress. A total of 18 major experiments were developed to generate the levels of biomass production of forage oats and ryegrass, determining 32 variables or parameters for each crop that requires the model to estimate the biomass produced by the forage and pasture. Furthermore, the engine for determining crop production handling model is the concept of crop water productivity (WP) which is a conservative parameter resulting in greater strength, besides water productivity is normalized in two ways: (1) the climate are represented by the reference evapotranspiration (ET0) and (2) the content of CO2 in the atmosphere. These normalization allow abstract both climate and CO2 content over time, whereby, the engine model turns out to be an essential tool to estimate both the biomass and production, even considering the effects of global climate change. The experiments were conducted mainly during the years 2008-2013 in “Centro de Investigación Tibaitatá (AGROSAVIA)” located in the savannah of Bogota (Colombia). For forage oats were developed five cycles and ryegrass crops three complete cycles, with seven, four and two cuts were made respectively. Based on the information provided in the field, forage oats and ryegrass crops were calibrated and validated for AquaCrop model reaching adjustments R2=0.92, RMSE=1,86t.ha-1, NRMSE=17.67%, EF=0.91, d=0.97 for forage oat and R2=0.97, RMSE=0,47t.ha-1, NRMSE=13.6%, EF=0.88, d=0.98 for ryegrass. Two synthetic crops were determined one for each specie, which are "prototypes" for estimating biomass by the water use in different conditions of crops. The total biomass was determined to forage oats at 22.2 t.ha-1 on average with peaks that can reach up to 27 t.ha-1 in the production environment of the savannah of Bogota. For ryegrass total biomass reached levels of up to 9 t.ha-1 on average with peaks that can reach up to 9,9 t.ha-1 for the period from planting to first cut, and 6 t.ha-1 for others cuts. The intrinsic water footprint for fodder oats was determined in 175 L.kg-1 and 442 ryegrass L.kg-1 and 431 L.Kg-1. This research is novel because implemented scientific and technological advances of AquaCrop in forage crops, for the determination of the biomass by the water, because until this had not been calibrated and validated for the model, special biophysical considerations forage crops driving differently elements like crop production and harvest index. In addition to the large expanses of areas that exist today in the world of forages and pastures, which can be incorporated into local, regional or global studies biomass production, efficient water use, water consumption and determination of requirements, carbon sequestration, and determining the effects of changes in the coverage of pasture and forage in the global climate change. Resumen: El objetivo principal estuvo orientado a la determinación de la producción de biomasa a partir del agua con base en las relaciones hídricas, los niveles de consumo de agua de las especies, y las variables del clima que inciden en la formación de biomasa y el suelo presentes y se centró específicamente en dos cultivos forrajeros: Avena Forrajera (Avena sativa, L.) y Raigrás (Lolium perenne). La solución al problema se basa en el modelo AquaCrop (FAO) Steduto et al, (2009) el cual fue propuesto para la determinación tanto de la biomasa como del rendimiento a partir del agua transpirada por las especies herbáceas, en este se reúnen los avances científicos y tecnológicos que sobre el efecto del agua en la estimación de la producción de cultivos se ha logrado en los últimos años. En el presente trabajo de investigación se han parametrizado las variables de entrada al modelo AquaCrop, para las dos especies mencionadas, por medio de investigación de campo realizada con la metodología del gradiente de Hanks et al, (1980), y con una nueva metodología propuesta para la determinación del estrés hídrico. Se desarrollaron un total de 18 experimentos principales generando los niveles de producción de biomasa de avena forrajera y raigrás, determinando 32 parámetros para cada uno de los cultivos que requiere el modelo para la estimación de la biomasa producida por las especies forrajeras y pastos. El modelo AquaCrop implementa varios avances sobre el conocimiento del desarrollo de cultivos, como la separación de la evapotranspiración en evaporación del suelo y la transpiración del cultivo, la consideración independiente de la producción del cultivo en biomasa y el índice de cosecha. Para la determinación del desarrollo del cultivo se maneja el porcentaje de cobertura del dosel en vez del índice de área foliar (IAF). Además, el motor para la determinación de la producción del cultivo que maneja el modelo es el concepto de la productividad hídrica del cultivo (WP) la cual es un parámetro conservativo que redunda en mayor robustez, la productividad hídrica además se normaliza bajo dos aspectos que son el clima representado por la evapotranspiración de referencia (ET0) y el contenido del CO2 en la atmósfera. Con base en la información establecida en campo se calibraron y validaron los cultivos de avena forrajera y raigrás para el modelo AquaCrop alcanzando ajustes de R2=0,92, RMSE=1,86t.ha-1, NRMSE=17,67%, EF=0,91, y d=0,97 para avena forrajera y de R2=0,97, RMSE=0,47t.ha-1, NRMSE=13,6%, EF=0,88, y d=0,98 para raigrás. Se determinaron dos cultivos sintéticos uno para cada especie, los cuales constituyen los “prototipos” que son el punto de partida para la estimación de la biomasa a partir del uso del agua en diferentes condiciones de los cultivos mencionados. La biomasa total para avena forrajera fue determinada en 22,2t.ha-1 en promedio con valores máximos que pueden llegar a alcanzar hasta 27t.ha-1 en el entorno productivo de la sabana de Bogotá. Para raigrás la biomasa total alcanzó niveles de hasta 9t.ha-1, para el período de siembra a primer corte, y de 6t.ha-1 para los cortes posteriores al primero. La huella hídrica intrínseca para avena forrajera fue determinada en 175L.kg-1 y para raigrás en 442L.kg-1 y 431L.Kg-1. El presente trabajo es novedoso por la implementación de los avances científicos y tecnológicos de AquaCrop en cultivos forrajeros, para la determinación de la biomasa a partir del agua, pues hasta la presente no habían sido calibrados y validados para el modelo, las consideraciones biofísicas especiales de los cultivos forrajeros que manejan de forma diferente elementos como la producción de cosecha y el índice de cosecha. Además por las grandes extensiones de áreas que existen hoy en el mundo de cultivos forrajeros y pastos, las cuales pueden ser incorporadas en estudios locales, regionales o globales de producción de biomasa, eficiencia en el uso del agua, consumos y determinación de requerimientos hídricos, captura de carbono, y determinación de los efectos de las variaciones de las coberturas de pastos y forrajes en el cambio climático global.
Fuente: Biblioteca Virtual Banco de la República Formatos de contenido: Tesis
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Determinación de la huella hídrica y modelación de la producción de biomasa de cultivos forrajeros a partir del agua en la sabana de Bogotá (Colombia)

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Imagen de apoyo de  Hypoxia Differentially Affects Healthy Men and Women During a Daytime Nap With a Dose-Response Relationship: a Randomized, Cross-Over Pilot Study

Hypoxia Differentially Affects Healthy Men and Women During a Daytime Nap With a Dose-Response Relationship: a Randomized, Cross-Over Pilot Study

Por: Alain; Penzel Riveros-Rivera | Fecha: 2022

Abstract: Context: Whether due to geopolitical instability, as in Colombia or Venezuela, global warming, or simply tourism, the movement of lowlanders to high altitudes is increasing. This population movement is accompanied by increased symptoms of physiological deconditioning, among which sleep disturbances stand out. In this scenario, napping is a counter measurement for sleep disturbances; however, its benefits or physiological changes at high altitudes have not been explored. Objective: To evaluate the physiological changes during a nap in conditions simulating high altitude. Methods: Randomized, single-blind, three period cross-over pilot study conducted with 15 healthy lowlander subjects (8 women) with a mean (SD) age of 29(6) years. Volunteers underwent an evaluation around a 90 min midday nap, being allocated to a randomized sequence of three conditions: FiO2 21% (NN), FiO2 14.7% (NH15) and 12.5% (NH13). Results: Compared to NN, RR during napping was shortened by 57 and 206 ms under NH15 and NH13 conditions, respectively (p <0.001). Sympathetic predominance was evident by HRV and increased epinephrine levels. Concomitantly, there were significant changes in endocrine parameters such as EPO (~6 UI/L) and cortisol (~100 nmol/L) (NH13 vs. NN, p < 0.001). Cognitive evaluation revealed changes in the color-word Stroop test. Although sleep efficiency was preserved, polysomnography showed lesser N3 and REM sleep, and periodic breathing, predominantly in men. Conclusions: although napping may have metabolic and cognitive benefits, its implementation as a counter measurement in conditions of altitudinal hypoxia should be carefully evaluated as it could increase the occurrence of sleep disturbances with consequences on autonomic, endocrine and respiratory systems. Abstract: Context: Whether due to geopolitical instability, as in Colombia or Venezuela, global warming, or simply tourism, the movement of lowlanders to high altitudes is increasing. This population movement is accompanied by increased symptoms of physiological deconditioning, among which sleep disturbances stand out. In this scenario, napping is a counter measurement for sleep disturbances; however, its benefits or physiological changes at high altitudes have not been explored. Objective: To evaluate the physiological changes during a nap in conditions simulating high altitude. Methods: Randomized, single-blind, three period cross-over pilot study conducted with 15 healthy lowlander subjects (8 women) with a mean (SD) age of 29(6) years. Volunteers underwent an evaluation around a 90 min midday nap, being allocated to a randomized sequence of three conditions: FiO2 21% (NN), FiO2 14.7% (NH15) and 12.5% (NH13). Results: Compared to NN, RR during napping was shortened by 57 and 206 ms under NH15 and NH13 conditions, respectively (p <0.001). Sympathetic predominance was evident by HRV and increased epinephrine levels. Concomitantly, there were significant changes in endocrine parameters such as EPO (~6 UI/L) and cortisol (~100 nmol/L) (NH13 vs. NN, p < 0.001). Cognitive evaluation revealed changes in the color-word Stroop test. Although sleep efficiency was preserved, polysomnography showed lesser N3 and REM sleep, and periodic breathing, predominantly in men. Conclusions: although napping may have metabolic and cognitive benefits, its implementation as a counter measurement in conditions of altitudinal hypoxia should be carefully evaluated as it could increase the occurrence of sleep disturbances with consequences on autonomic, endocrine and respiratory systems. Resumen: Contexto: Ya sea por inestabilidad geopolítica, como ocurre en Colombia o Venezuela, por el calentamiento global, o simplemente por turismo, cada vez el desplazamiento de nativos de bajas alturas hacia las grandes alturas es mayor. Este movimiento poblacional se acompaña de un incremento en síntomas de desacondicionamiento fisiológico dentro de los que destacan las perturbaciones del sueño. En este escenario la siesta aparece como una medida contrarreguladora para las alteraciones del sueño; sin embargo, sus beneficios o cambios fisiológicos en las grandes alturas no ha sido explorado. Objetivo: Evaluar los cambios fisiológicos durante una siesta en condiciones que simulan la altura. Metodología: Este fue un estudio piloto aleatorizado, ciego, cruzado llevado a cabo con 15 sujetos nativos de bajas alturas (8 mujeres) con una edad promedio de 29 años (D.E.=6 años). Los voluntarios fueron evaluados fisiológicamente alrededor a una siesta de aproximadamente 90 min, siendo dispuestos en una secuencia aleatoria de tres condiciones: FiO2 de 21% (NN), FiO2 de 14,7% (NH15) y de 12,5% (NH13), con un periodo de reposo entre condiciones de una semana. Resultados: Comparado con NN, los intervalor RR durante la siesta se acortaron significativamente (p < 0,001) en 57 ms (NH15) y 206 ms (NH13). El predominio simpático fue evidente por el análisis de la variabilidad de frecuencia cardiaca y los niveles aumentados de adrenalina. Concomitántemente, hubo cambios significativos en parámetros endocrinos tales como al eritropoyetina (~6 UI/L) y cortisol (~100 nmol/L) (NH13 VS. NN, p < 0,001). La evaluación cognitiva mostró cambios en la prueba de Stroop. Adicionalmente, aunque la eficiencia del sueño se preservó, los resultados polisomnográficos mostraron una disminución en el sueño profundo y MOR, y un incremento de respiración periódica, fundamentalmente en hombres. Conclusiones: aunque tomar la siesta pueda tener beneficios metabólicos y cognitivos, su implementación como contrarreguladora en condiciones de hipoxia altitudinal debe ser evaluada cuidadosamente ya que podría incrementar la aparición de perturbaciones del sueño con efectos en los sistemas autónomo, endocrino y respiratorio.
Fuente: Biblioteca Virtual Banco de la República Formatos de contenido: Artículos
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Hypoxia Differentially Affects Healthy Men and Women During a Daytime Nap With a Dose-Response Relationship: a Randomized, Cross-Over Pilot Study

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Imagen de apoyo de  Evaluación de vibraciones en el diagnóstico de estructuras: estudio de comportamiento de estructuras en deterioro = Vibration evaluation in the diagnosis of structures: Study of behaviour of deteriorating structures

Evaluación de vibraciones en el diagnóstico de estructuras: estudio de comportamiento de estructuras en deterioro = Vibration evaluation in the diagnosis of structures: Study of behaviour of deteriorating structures

Por: Angel Eduard Rodríguez Suesca | Fecha: 2021

Resumen: La respuesta dinámica de una estructura a lo largo de su vida útil varia debido al deterioro causado por diferentes factores, siendo los agentes ambientales y las cargas los causantes principales de degradación. Las acciones dinámicas representan uno de los mayores causantes de daño, evidenciado en fenómenos fatiga, microfisuración, agrietamiento, plastificación, desprendimiento y hasta colapso. Este daño puede ser usualmente mínimo para cargas de servicio y severo para el caso de cargas dinámicas extraordinarias de alta intensidad (impactos, sismos, explosiones, viento fuerte). La interacción entre las acciones y la respuesta también puede ocasionar daños importantes como en el caso de cargas moderadas de servicio con amplificación de la respuesta por fenómenos de resonancia. En la práctica, la evaluación del estado de las estructuras se basa principalmente en observaciones visuales y se describe mediante índices subjetivos que no permiten un diagnóstico preciso del comportamiento, la capacidad de servicio y la seguridad. Una evaluación confiable del comportamiento dinámico de una estructura depende de información cuantitativa más que cualitativa, por lo que, existe actualmente una necesidad para desarrollar metodologías de diagnóstico que incluyan parámetros de cuantificación de daño basados en pruebas directas de la respuesta vibratoria. Dentro de la gestión de infraestructura, un proceso más objetivo y confiable para la evaluación y cuantificación del estado de deterioro de las estructuras es requerido para ser utilizado en inspecciones rutinarias dirigidas al control, mantenimiento y rehabilitación. La presente tesis estudia las metodologías de evaluación experimental de la respuesta vibratoria aplicadas al diagnóstico de estructuras en deterioro, buscando prácticas estandarizadas de diagnóstico que determinen con confianza el grado de cumplimiento, deterioro o severidad del daño de una estructura, tanto para casos de carga extrema como para condiciones de operación normal. Las contribuciones fundamentales parten del estudio experimental de la degradación de las propiedades de un modelo estructural de laboratorio sometido a la acción de fuerzas dinámicas y se desarrollan ampliamente con la ejecución de dos investigaciones experimentales profundas de estructuras reales con un grado evidente de deterioro. Se comparan las técnicas de diagnóstico directo por inspección del daño contra las técnicas basadas en vibración. Diferentes formas de cuantificación del daño, el deterioro, la calidad y la incomodidad fueron propuestos. El desarrollo del trabajo doctoral parte de una síntesis de las bases y aplicaciones de la predicción, medición y análisis de las vibraciones en estructuras, enfocada a generar herramientas de diagnóstico para la implementación en pruebas rutinarias de evaluación para condiciones de servicio y de seguridad. En este sentido, se muestran ejemplos prácticos que ilustran de mejor manera los conceptos involucrados. Se describen las herramientas para la identificación de propiedades dinámicas y de cuantificación del daño basada en pruebas de vibración.
Fuente: Biblioteca Virtual Banco de la República Formatos de contenido: Tesis
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Evaluación de vibraciones en el diagnóstico de estructuras: estudio de comportamiento de estructuras en deterioro = Vibration evaluation in the diagnosis of structures: Study of behaviour of deteriorating structures

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Imagen de apoyo de  Can We Predict Emotion Regulation, Attachment, Impulsivity And Empathy From Lysergic Acid Diethylamide Use? Towards The Use Of Serotonergic Psychedelics In The Treatment For Sociopathy

Can We Predict Emotion Regulation, Attachment, Impulsivity And Empathy From Lysergic Acid Diethylamide Use? Towards The Use Of Serotonergic Psychedelics In The Treatment For Sociopathy

Por: Andrea Nicole Alarcón Bello | Fecha: 2021

Abstract: Characteristic traits of sociopathy, like emotion dysregulation, lack of perspective taking and impulsivity, seem to be grounded in early social experiences of abuse/maltreatment and insecure attachment (Yildirim & Derksen, 2013). These characteristics have been related to the maturation and functionality of the ventromedial prefrontal cortex (vmPFC) and the orbitofrontal cortex (OFC), which are strongly regulated by serotonin (Yildirim & Derksen, 2013). This study aims to explore whether some characteristics of sociopathy can be predicted by the use of a potent serotonergic agonist, Lysergic acid diethylamide (LSD), in the general population. Participants completed emotion regulation, impulsivity, empathy and attachment measures, and answered queries about different aspects of LSD use. Multiple linear regression analyses (n = 81) showed that different LSD use variables predicted attachment-related avoidance (R2 = .26), reappraisal (R2 = .18), personal distress (R2 = .21), empathic concern (R2 = .31), positive urgency (R2 = .23), sensation seeking (R2 = .35), and negative urgency (R2 = .19), with ?s ranging from |0.221| to |0.471|. This study is one first step towards using serotonergic psychedelics for treating sociopathy, but semi-experimental longitudinal studies are needed to tell if the relations found here are causal. If this is true, psychedelics could be used in conjunction with psychotherapy for improving mental health in emotion dysregulation disorders and for preventing further antisocial behaviours in people with sociopathic profiles. Finally, I discuss the implications of these results for Colombia, a country that has been fraught in conflict for more than 50 years.
Fuente: Biblioteca Virtual Banco de la República Formatos de contenido: Tesis
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Can We Predict Emotion Regulation, Attachment, Impulsivity And Empathy From Lysergic Acid Diethylamide Use? Towards The Use Of Serotonergic Psychedelics In The Treatment For Sociopathy

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